Development of a DNA Microarray for Toxicology Based on Hepatotoxin-Regulated Sequences

Toxicogenomics is an emerging field combining genomics and bioinformatics to identify and characterize mechanisms of toxicity of compounds. One of the main tools used in toxicogenomics is DNA microarrays. We have used a novel strategy to create a library highly enriched for genes expressed in the li...

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Veröffentlicht in:	Environmental health perspectives 2003-05, Vol.111 (6), p.863-870
Hauptverfasser:	Waring, Jeffrey F., Cavet, Guy, Jolly, Robert A., McDowell, Jeff, Dai, Hongye, Ciurlionis, Rita, Zhang, Chunsheng, Stoughton, Roland, Lum, Pek, Ferguson, Allan, Roberts, Christopher J., Ulrich, Roger G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene expression regulation Genes Libraries Liver Oligonucleotide probes Polychlorinated biphenyls Rats RNA Toxicity Toxicogenomics Toxicology
Online-Zugang:	Volltext
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