Application of Biologically Based Computer Modeling to Simple or Complex Mixtures

The complexity and the astronomic number of possible chemical mixtures preclude any systematic experimental assessment of toxicology of all potentially troublesome chemical mixtures. Thus, the use of computer modeling and mechanistic toxicology for the development of a predictive tool is a promising...

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Veröffentlicht in:	Environmental health perspectives 2002-12, Vol.110 (suppl 6), p.957-963
Hauptverfasser:	Liao, Kai H., Dobrev, Ivan D., Dennison, James E., Andersen, Melvin E., Reisfeld, Brad, Reardon, Kenneth F., Campain, Julie A., Wei Wei, Klein, Michael T., Quann, Richard J., Raymond S. H. Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Application of Computer and Statistical Modeling to Chemical Mixtures Chemical hazards Chemical mixtures Computer Simulation Dose-Response Relationship, Drug Drug design Drug Interactions Environmental Pollutants - adverse effects Forecasting Kinetics Metabolism Modeling Molecules Petroleum Pharmacokinetics Reactants Risk Assessment Toxicology Xenobiotics - adverse effects
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