TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium

Dictyostelium cells form a multicellular organism through the aggregation of independent cells. This process requires both chemotaxis and signal relay in which the chemoattractant cAMP activates adenylyl cyclase through the G protein-coupled cAMP receptor cAR1. cAMP is produced and secreted and it a...

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Veröffentlicht in:	Molecular biology of the cell 2005-10, Vol.16 (10), p.4572-4583
Hauptverfasser:	Lee, Susan, Comer, Frank I, Sasaki, Atsuo, McLeod, Ian X, Duong, Yung, Okumura, Koichi, Yates, 3rd, John R, Parent, Carole A, Firtel, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Carrier Proteins - genetics Cell Cycle Proteins - genetics Cell Polarity Chemotaxis Cyclic AMP - metabolism Dictyostelium Dictyostelium - genetics Dictyostelium - physiology Enzyme Activation Intracellular Signaling Peptides and Proteins - genetics Molecular Sequence Data Mutation Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Phosphorylation Proto-Oncogene Proteins c-akt - metabolism Protozoan Proteins - genetics Protozoan Proteins - metabolism Receptors, Cyclic AMP Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins - genetics Sequence Homology, Amino Acid Signal Transduction
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