Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues
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Veröffentlicht in: | Molecular and Cellular Biology 2005-09, Vol.25 (18), p.8299-8310 |
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creator | Klement, John F. Matsuzaki, Yasushi Jiang, Qiu-Jie Terlizzi, Joseph Choi, Hae Young Fujimoto, Norihiro Li, Kehua Pulkkinen, Leena Birk, David E. Sundberg, John P. Uitto, Jouni |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.25.18.8299-8310.2005</identifier><identifier>PMID: 16135817</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Animals ; ATP-Binding Cassette Transporters - genetics ; Biomarkers ; Calcinosis - etiology ; Calcinosis - pathology ; Connective Tissue - pathology ; Connective Tissue - ultrastructure ; Disease Models, Animal ; Fibrillar Collagens - ultrastructure ; Gene Silencing ; Gene Targeting ; Mammalian Genetic Models with Minimal or Complex Phenotypes ; Mice ; Mice, Transgenic ; Minerals - metabolism ; Multidrug Resistance-Associated Proteins ; Pseudoxanthoma Elasticum - etiology ; Pseudoxanthoma Elasticum - genetics ; Pseudoxanthoma Elasticum - pathology ; Skin - diagnostic imaging ; Skin - pathology ; Tomography, X-Ray Computed ; Vibrissae - pathology ; Vibrissae - ultrastructure</subject><ispartof>Molecular and Cellular Biology, 2005-09, Vol.25 (18), p.8299-8310</ispartof><rights>Copyright © 2005, American Society for Microbiology 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c657t-f6c91d5119e6a691a6a13b3c41686759a1e76d4c9b924278bc9ed59d092d6e73</citedby><cites>FETCH-LOGICAL-c657t-f6c91d5119e6a691a6a13b3c41686759a1e76d4c9b924278bc9ed59d092d6e73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234326/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234326/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16135817$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Klement, John F.</creatorcontrib><creatorcontrib>Matsuzaki, Yasushi</creatorcontrib><creatorcontrib>Jiang, Qiu-Jie</creatorcontrib><creatorcontrib>Terlizzi, Joseph</creatorcontrib><creatorcontrib>Choi, Hae Young</creatorcontrib><creatorcontrib>Fujimoto, Norihiro</creatorcontrib><creatorcontrib>Li, Kehua</creatorcontrib><creatorcontrib>Pulkkinen, Leena</creatorcontrib><creatorcontrib>Birk, David E.</creatorcontrib><creatorcontrib>Sundberg, John P.</creatorcontrib><creatorcontrib>Uitto, Jouni</creatorcontrib><title>Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Animals</subject><subject>ATP-Binding Cassette Transporters - genetics</subject><subject>Biomarkers</subject><subject>Calcinosis - etiology</subject><subject>Calcinosis - pathology</subject><subject>Connective Tissue - pathology</subject><subject>Connective Tissue - ultrastructure</subject><subject>Disease Models, Animal</subject><subject>Fibrillar Collagens - ultrastructure</subject><subject>Gene Silencing</subject><subject>Gene Targeting</subject><subject>Mammalian Genetic Models with Minimal or Complex Phenotypes</subject><subject>Mice</subject><subject>Mice, Transgenic</subject><subject>Minerals - metabolism</subject><subject>Multidrug Resistance-Associated Proteins</subject><subject>Pseudoxanthoma Elasticum - etiology</subject><subject>Pseudoxanthoma Elasticum - genetics</subject><subject>Pseudoxanthoma Elasticum - pathology</subject><subject>Skin - diagnostic imaging</subject><subject>Skin - pathology</subject><subject>Tomography, X-Ray Computed</subject><subject>Vibrissae - pathology</subject><subject>Vibrissae - ultrastructure</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkV9rFDEUxYModq1-BQk--DZr_kwyyYtQh1qFFkH2zYeQydzZjcwka5JtaT-9M-xS65M-hBDu75x7wkEIU7KmlKkPN-2nNRNrqtaKaV0pPg8YIeIZWlGiVSVErZ-jFWENqRpO5Bl6lfNPQojUhL9EZ1RSLhRtVujHxqYtFOjxRTfa4mPAccBlB_PbOYmvIAD-Dvkwlox9wJeuxL13-MYHSHb0D4-aNoYArvhbwBuf8wHya_RisGOGN6f7HG0-X27aL9X1t6uv7cV15aRoSjVIp2kvKNUgrdTUSkt5x11NpZKN0JZCI_va6U6zmjWqcxp6oXuiWS-h4efo49F2f-gm6B2EMicz--Qnm-5NtN78PQl-Z7bx1lDGa87kbPD-ZJDirzl3MZPPDsbRBoiHbKQS9XL-CdKmpoQzMoPqCLoUc04wPKahxCwNmrlBw4ShyiwNmqVBszQ4S98-_c0f4amyGWiPgA9DTJO9i2nsTbH3Y0xDssH5bPh_rHl3dNn57e7OJzA2T2Zy3ROc_waPUbj0</recordid><startdate>20050901</startdate><enddate>20050901</enddate><creator>Klement, John F.</creator><creator>Matsuzaki, Yasushi</creator><creator>Jiang, Qiu-Jie</creator><creator>Terlizzi, Joseph</creator><creator>Choi, Hae Young</creator><creator>Fujimoto, Norihiro</creator><creator>Li, Kehua</creator><creator>Pulkkinen, Leena</creator><creator>Birk, David E.</creator><creator>Sundberg, John P.</creator><creator>Uitto, Jouni</creator><general>American Society for Microbiology</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20050901</creationdate><title>Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues</title><author>Klement, John F. ; Matsuzaki, Yasushi ; Jiang, Qiu-Jie ; Terlizzi, Joseph ; Choi, Hae Young ; Fujimoto, Norihiro ; Li, Kehua ; Pulkkinen, Leena ; Birk, David E. ; Sundberg, John P. ; Uitto, Jouni</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c657t-f6c91d5119e6a691a6a13b3c41686759a1e76d4c9b924278bc9ed59d092d6e73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>ATP-Binding Cassette Transporters - genetics</topic><topic>Biomarkers</topic><topic>Calcinosis - etiology</topic><topic>Calcinosis - pathology</topic><topic>Connective Tissue - pathology</topic><topic>Connective Tissue - ultrastructure</topic><topic>Disease Models, Animal</topic><topic>Fibrillar Collagens - ultrastructure</topic><topic>Gene Silencing</topic><topic>Gene Targeting</topic><topic>Mammalian Genetic Models with Minimal or Complex Phenotypes</topic><topic>Mice</topic><topic>Mice, Transgenic</topic><topic>Minerals - metabolism</topic><topic>Multidrug Resistance-Associated Proteins</topic><topic>Pseudoxanthoma Elasticum - etiology</topic><topic>Pseudoxanthoma Elasticum - genetics</topic><topic>Pseudoxanthoma Elasticum - pathology</topic><topic>Skin - diagnostic imaging</topic><topic>Skin - pathology</topic><topic>Tomography, X-Ray Computed</topic><topic>Vibrissae - pathology</topic><topic>Vibrissae - ultrastructure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Klement, John F.</creatorcontrib><creatorcontrib>Matsuzaki, Yasushi</creatorcontrib><creatorcontrib>Jiang, Qiu-Jie</creatorcontrib><creatorcontrib>Terlizzi, Joseph</creatorcontrib><creatorcontrib>Choi, Hae Young</creatorcontrib><creatorcontrib>Fujimoto, Norihiro</creatorcontrib><creatorcontrib>Li, Kehua</creatorcontrib><creatorcontrib>Pulkkinen, Leena</creatorcontrib><creatorcontrib>Birk, David E.</creatorcontrib><creatorcontrib>Sundberg, John P.</creatorcontrib><creatorcontrib>Uitto, Jouni</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Molecular and Cellular Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Klement, John F.</au><au>Matsuzaki, Yasushi</au><au>Jiang, Qiu-Jie</au><au>Terlizzi, Joseph</au><au>Choi, Hae Young</au><au>Fujimoto, Norihiro</au><au>Li, Kehua</au><au>Pulkkinen, Leena</au><au>Birk, David E.</au><au>Sundberg, John P.</au><au>Uitto, Jouni</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues</atitle><jtitle>Molecular and Cellular Biology</jtitle><addtitle>Mol Cell Biol</addtitle><date>2005-09-01</date><risdate>2005</risdate><volume>25</volume><issue>18</issue><spage>8299</spage><epage>8310</epage><pages>8299-8310</pages><issn>0270-7306</issn><issn>1098-5549</issn><eissn>1098-5549</eissn><abstract>Article Usage Stats
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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>16135817</pmid><doi>10.1128/MCB.25.18.8299-8310.2005</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Animals ATP-Binding Cassette Transporters - genetics Biomarkers Calcinosis - etiology Calcinosis - pathology Connective Tissue - pathology Connective Tissue - ultrastructure Disease Models, Animal Fibrillar Collagens - ultrastructure Gene Silencing Gene Targeting Mammalian Genetic Models with Minimal or Complex Phenotypes Mice Mice, Transgenic Minerals - metabolism Multidrug Resistance-Associated Proteins Pseudoxanthoma Elasticum - etiology Pseudoxanthoma Elasticum - genetics Pseudoxanthoma Elasticum - pathology Skin - diagnostic imaging Skin - pathology Tomography, X-Ray Computed Vibrissae - pathology Vibrissae - ultrastructure |
title | Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues |
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