[K+] dependence of open-channel conductance in cloned inward rectifier potassium channels (IRK1, Kir2.1)

Potassium conduction through unblocked inwardly rectifying (IRK1, Kir2.1) potassium channels was measured in inside-out-patches from Xenopus oocytes, after removal of polyamine-induced strong inward rectification. Unblocked IRK1 channel current-voltage (I-V) relations show very mild inward rectifica...

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Veröffentlicht in:	Biophysical journal 1996-08, Vol.71 (2), p.682-694
Hauptverfasser:	Lopatin, A.N., Nichols, C.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cloning, Molecular Female In Vitro Techniques Ion Channel Gating Kinetics Magnesium - pharmacology Mathematics Membrane Potentials - drug effects Models, Biological Oocytes - physiology Patch-Clamp Techniques Polyamines - pharmacology Potassium - metabolism Potassium - pharmacology Potassium Channels - biosynthesis Potassium Channels - drug effects Potassium Channels - physiology Potassium Channels, Inwardly Rectifying Recombinant Proteins - biosynthesis Recombinant Proteins - drug effects Recombinant Proteins - metabolism Xenopus
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