The POU homeodomain protein OCT3 as a potential transcriptional activator for fibroblast growth factor-4 (FGF-4) in human breast cancer cells

The POU (representing a homeodomain protein family of which the founder members are Pit-1, Oct-1/2 and Unc-86) homeodomain protein OCT3/Oct-3 (where OCT stands for octamer-binding protein) is an embryonic transcription factor expressed in oocytes, embryonic stem and embryonic carcinoma cells. We hav...

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Veröffentlicht in:	Biochemical journal 2003-10, Vol.375 (Pt 1), p.199-205
Hauptverfasser:	Wang, Peixiang, Branch, Donald R, Bali, Meenakshi, Schultz, Gilbert A, Goss, Paul E, Jin, Tianru
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Blotting, Western Breast Neoplasms - genetics Breast Neoplasms - metabolism Cell Line DNA-Binding Proteins - metabolism Down-Regulation Female Fibroblast Growth Factor 4 Fibroblast Growth Factors - biosynthesis Fibroblast Growth Factors - genetics Gene Expression Regulation, Neoplastic Humans Octamer Transcription Factor-3 Promoter Regions, Genetic Proto-Oncogene Proteins - biosynthesis Proto-Oncogene Proteins - genetics Response Elements Thymidine Kinase - genetics Transcription Factors - metabolism Transcriptional Activation Tretinoin - pharmacology Tumor Cells, Cultured
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