Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme

Angiotensin I-converting enzyme (ACE) is a highly glycosylated type I integral membrane protein. A series of underglycosylated testicular ACE (tACE) glycoforms, lacking between one and five N-linked glycosylation sites, were used to assess the role of glycosylation in tACE processing, crystallizatio...

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Veröffentlicht in:	Biochemical journal 2003-04, Vol.371 (Pt 2), p.437-442
Hauptverfasser:	Gordon, Kerry, Redelinghuys, Pierre, Schwager, Sylva L U, Ehlers, Mario R W, Papageorgiou, Anastassios C, Natesh, Ramanathan, Acharya, K Ravi, Sturrock, Edward D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CHO Cells Cricetinae Crystallization Glycosylation Humans Kinetics Male Mutagenesis, Site-Directed Peptidyl-Dipeptidase A - chemistry Peptidyl-Dipeptidase A - isolation & purification Peptidyl-Dipeptidase A - metabolism Recombinant Proteins - chemistry Recombinant Proteins - metabolism Testis - enzymology
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