Transport of phosphatidylserine via MDR1 (multidrug resistance 1)P-glycoprotein in a human gastric carcinoma cell line

The ATP-binding cassette transporter multidrug resistance 1 P-glycoprotein (MDR1 Pgp) has been implicated with the transport of lipids from the inner to the outer leaflet of the plasma membrane. While this has been unambigously shown for the fluorescent lipid analogues [N-(7-nitrobenz-2-oxa-1,3-diaz...

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Veröffentlicht in:	Biochemical journal 2002-07, Vol.365 (Pt 1), p.259-268
Hauptverfasser:	Pohl, Antje, Lage, Hermann, Müller, Peter, Pomorski, Thomas, Herrmann, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Chloro-7-nitrobenzofurazan - analogs & derivatives 4-Chloro-7-nitrobenzofurazan - metabolism ATP-Binding Cassette, Sub-Family B, Member 1 - genetics ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism Biological Transport, Active Cell Membrane - metabolism Gene Expression Humans Kinetics Phosphatidylcholines - metabolism Phosphatidylethanolamines - metabolism Phosphatidylserines - metabolism Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Tumor Cells, Cultured
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