Transcriptional and translational mechanisms of cytochrome b5 reductase isoenzyme generation in humans

Cytochrome b5 reductase (b5R) is an essential enzyme that exists in soluble and membrane-bound isoforms, each with specific functions. In the rat, the two forms are generated from alternative transcripts differing in the first exons. In contrast, the biogenesis of b5R isoforms in the human is not ye...

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Veröffentlicht in:	Biochemical journal 2001-04, Vol.355 (Pt 2), p.529-535
Hauptverfasser:	Leroux, A, Mota Vieira, L, Kahn, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Amino Acid Sequence Animals Base Sequence Cytochrome Reductases - genetics Cytochrome-B Reductase Fetal Blood - enzymology Humans Isoenzymes - genetics Liver - embryology Liver - enzymology Lymphocytes - enzymology Molecular Sequence Data Nucleic Acid Hybridization Protein Biosynthesis Rats Reticulocytes - enzymology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Transcription, Genetic
Online-Zugang:	Volltext
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