Identification, characterization and leucocyte expression of Siglec-10, a novel human sialic acid-binding receptor

Here we characterize Siglec-10 as a new member of the Siglec family of sialic acid-binding Ig-like lectins. A full-length cDNA was isolated from a human spleen library and the corresponding gene identified. Siglec-10 is predicted to contain five extracellular Ig-like domains and a cytoplasmic tail c...

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Veröffentlicht in:	Biochemical journal 2001-04, Vol.355 (Pt 2), p.489-497
Hauptverfasser:	Munday, J, Kerr, S, Ni, J, Cornish, A L, Zhang, J Q, Nicoll, G, Floyd, H, Mattei, M G, Moore, P, Liu, D, Crocker, P R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Chromosome Mapping Chromosomes, Human, Pair 19 DNA Primers DNA, Complementary Humans Lectins - chemistry Lectins - genetics Lectins - metabolism Leukocytes - metabolism Molecular Sequence Data Phylogeny Receptors, Cell Surface Sequence Homology, Amino Acid
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