Biogenesis of endoplasmic reticulum proteins involved in Ca2+ signalling during megakaryocytic differentiation: an in vitro study

The endoplasmic reticulum (ER) plays a key role in Ca(2+) signalling through Ca(2+) release via inositol 1,4,5-trisphosphate receptors (InsP(3)-Rs) and Ca(2+) uptake by sarco/endoplasmic reticulum Ca(2+)-ATPases (SERCAs). Here, we investigated the organization of platelet ER and its biogenesis durin...

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Veröffentlicht in:	Biochemical journal 2000-09, Vol.350 Pt 3 (3), p.723-734
Hauptverfasser:	Lacabaratz-Porret, C, Launay, S, Corvazier, E, Bredoux, R, Papp, B, Enouf, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Signaling Calcium-Transporting ATPases - metabolism Cell Differentiation - drug effects Endoplasmic Reticulum - metabolism Fluorescent Antibody Technique Humans Megakaryocytes - cytology Tetradecanoylphorbol Acetate - pharmacology
Online-Zugang:	Volltext
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