S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme

An enzyme isolated from rat liver cytosol (native molecular mass 78. 3 kDa; polypeptide molecular mass 42.5 kDa) is capable of catalysing the NADH/NADPH-dependent degradation of S-nitrosoglutathione (GSNO). The activity utilizes 1 mol of coenzyme per mol of GSNO processed. The isolated enzyme has, a...

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Veröffentlicht in:	Biochemical journal 1998-04, Vol.331 ( Pt 2) (2), p.659-668
Hauptverfasser:	Jensen, D E, Belka, G K, Du Bois, G C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Dehydrogenase - chemistry Alcohol Dehydrogenase - metabolism Amino Acid Sequence Animals Cytosol - enzymology Glutathione - analogs & derivatives Glutathione - metabolism Isoenzymes - chemistry Isoenzymes - metabolism Kinetics Lauric Acids - metabolism Liver - enzymology Molecular Sequence Data NAD - pharmacology Nitroso Compounds - metabolism Octanols - metabolism Rats S-Nitrosoglutathione Substrate Specificity
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