Insulin-like growth factor I stimulates degradation of an mRNA transcript encoding the 14 kDa ubiquitin-conjugating enzyme

Upon fasting, the ubiquitin-dependent proteolytic system is activated in skeletal muscle in parallel with the increases in rates of proteolysis. Levels of mRNA encoding the 14 kDa ubiquitin-conjugating enzyme (E2(14K)), which can catalyse the first irreversible reaction in this pathway, rise and fal...

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Veröffentlicht in:	Biochemical journal 1996-10, Vol.319 ( Pt 2) (2), p.455-461
Hauptverfasser:	Wing, S S, Bedard, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Insulin-Like Growth Factor I - pharmacology Ligases - metabolism Mice Muscle, Skeletal - enzymology RNA, Messenger - drug effects RNA, Messenger - metabolism Ubiquitin-Conjugating Enzymes
Online-Zugang:	Volltext
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