Roles of insulin, guanosine 5'-[gamma-thio]triphosphate and phorbol 12-myristate 13-acetate in signalling pathways of GLUT4 translocation

Insulin, guanosine 5'-[gamma-thio]triphosphate (GTP[S] and phorbol 12-myristate 13-acetate (PMA) trigger the translocation of Gl UT4 (type 4 glucose transporter; insulin-sensitive glucose transporter) from an intracellular pool to the cell surface. We have developed a highly sensitive and quant...

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Veröffentlicht in:	Biochemical journal 1996-05, Vol.315 ( Pt 3) (3), p.875-882
Hauptverfasser:	Todaka, M, Hayashi, H, Imanaka, T, Mitani, Y, Kamohara, S, Kishi, K, Tamaoka, K, Kanai, F, Shichiri, M, Morii, N, Narumiya, S, Ebina, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Biological Transport, Active - drug effects CHO Cells Cricetinae Glucose Transporter Type 4 GTP-Binding Proteins - genetics GTP-Binding Proteins - metabolism Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology Insulin - pharmacology Mice Models, Biological Monosaccharide Transport Proteins - metabolism Muscle Proteins Phosphatidylinositol 3-Kinases Phosphotransferases (Alcohol Group Acceptor) - metabolism Protein Kinase C - metabolism Signal Transduction - drug effects Tetradecanoylphorbol Acetate - pharmacology
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