Mismatch Correction Acts as a Barrier to Homeologous Recombination in Saccharomyces cerevisiae

A homeologous mitotic recombination assay was used to test the role of Saccharomyces cerevisiae mismatch repair genes PMS1, MSH2 and MSH3 on recombination fidelity. A homeologous gene pair consisting of S. cerevisiae SPT15 and its S. pombe homolog were present as a direct repeat on chromosome V, wit...

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Veröffentlicht in:	Genetics (Austin) 1995-03, Vol.139 (3), p.1175-1188
Hauptverfasser:	Selva, E. M, New, L, Crouse, G. F, Lahue, R. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Chromosomes - genetics Chromosomes - metabolism DNA Repair - genetics DNA-Binding Proteins - genetics Gene Deletion Genes Genetics Investigations Mitosis - genetics Molecular Sequence Data Mutation Recombination, Genetic - genetics Saccharomyces cerevisiae - genetics Sequence Homology, Nucleic Acid TATA-Box Binding Protein Transcription Factors - genetics Yeast
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