Dating the Primigenial C4-CYP21 Duplication in Primates

C4 and CYP21 are two adjacent, but functionally unrelated genes residing in the middle of the mammalian major histocompatibility complex (Mhc). The C4 gene codes for the fourth component of the complement cascade, whereas the CYP21 gene specifies an enzyme (cytochrome P450c21) of the glucocorticoid...

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Veröffentlicht in:	Genetics (Austin) 1993-05, Vol.134 (1), p.331-339
Hauptverfasser:	Horiuchi, Y, Kawaguchi, H, Figueroa, F, O'hUigin, C, Klein, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Biological Evolution Chromosome Mapping Complement C4 - genetics DNA - genetics Female Fundamental and applied biological sciences. Psychology Genetics Genetics of eukaryotes. Biological and molecular evolution Gorilla gorilla - genetics Humans Investigations Macaca nemestrina - genetics Mammals Molecular Sequence Data Multigene Family Pan troglodytes - genetics Pongo pygmaeus - genetics Primates Primates - genetics Sequence Homology, Nucleic Acid Species Specificity Steroid 21-Hydroxylase - genetics
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