DNA SEQUENCE ANALYSIS OF MUTAGENICITY AND SITE SPECIFICITY OF ETHYL METHANESULFONATE IN Uvr+ AND UvrB - STRAINS OF ESCHERICHIA COLI

EMS-induced mutations within a 180 base pair region of the lacI gene of E. coli were cloned and sequenced. In total, 105 and 79 EMS-induced mutations from a Uvr+ and a UvrB- strain, respectively, were sequenced. The specificity of EMS-induced mutagenesis was very similar in the two strains; G:C---A:...

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Veröffentlicht in:	Genetics (Austin) 1986-08, Vol.113 (4), p.811-819
Hauptverfasser:	Burns, Philip A, Allen, Frances L, Glickman, Barry W
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cloning, Molecular DNA, Bacterial - genetics Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - radiation effects Ethyl Methanesulfonate - pharmacology Genes, Bacterial - drug effects Investigations Mutation Species Specificity Ultraviolet Rays
Online-Zugang:	Volltext
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