Sodium channels in cultured cardiac cells

Primary cardiac cell cultures were prepared from the hearts of neonatal rats. The patch-clamp method (Hamill, Marty, Neher, Sakmann & Sigworth, 1981) was applied for studying whole-cell Na+ currents and single-channel Na+ currents, respectively. Whole-cell recordings yielded voltage- and time-de...

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Veröffentlicht in:	The Journal of physiology 1983-07, Vol.340 (1), p.389-401
Hauptverfasser:	Cachelin, A B, De Peyer, J E, Kokubun, S, Reuter, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Animals Cells, Cultured Ion Channels - drug effects Membrane Potentials - drug effects Myocardium - cytology Rats Sodium - physiology Tetrodotoxin - pharmacology
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