Cerebrospinal fluid concentrations of neuropeptide Y in depressed patients and in controls

Cerebrospinal fluid concentrations of neuropeptide Y in depressed patients and in controls

Concentrations of Neuropeptide Y-like (NPY-LI) immunoreactivity in cerebrospinal fluid (CSF) were measured in a group of depressed patients (n = 24) and compared with that of control subjects (n = 12). CSF-NPY-LI was significantly reduced in the group of non-endogenously depressed patients when clas...

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Veröffentlicht in:Journal of psychiatry & neuroscience 1992-03, Vol.17 (1), p.23-27
Hauptverfasser: Gjerris, A, Widerlöv, E, Werdelin, L, Ekman, R
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Depressive Disorder - cerebrospinal fluid
Depressive Disorder - diagnosis
Depressive Disorder - psychology
Female
Humans
Male
Middle Aged
Neuropeptide Y - cerebrospinal fluid
Neurotransmitter Agents - cerebrospinal fluid
Psychiatric Status Rating Scales
Radioimmunoassay
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Zusammenfassung:Concentrations of Neuropeptide Y-like (NPY-LI) immunoreactivity in cerebrospinal fluid (CSF) were measured in a group of depressed patients (n = 24) and compared with that of control subjects (n = 12). CSF-NPY-LI was significantly reduced in the group of non-endogenously depressed patients when classified according to Newcastle Rating Scale for Depression--1971 (N-II). No significant correlation was found in the control or depressed groups between lumbar concentrations of NPY-LI and a number of other neurotransmitters.
ISSN:1180-4882
1488-2434