The novel human MOST-1 (C8orf17) gene exhibits tissue specific expression, maps to chromosome 8q24.2, and is overexpressed/amplified in high grade cancers of the breast and prostate

Aims: To elucidate genes that participate in the process of oncogenesis, primers based on the E6 genes of genital human papillomaviruses (HPVs) were used to amplify potential expressed sequence tags (ESTs) from the MOLT-4 T lymphoblastic leukaemia cell line. Methods: Using the polymerase chain react...

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Veröffentlicht in:	Molecular pathology 2003-04, Vol.56 (2), p.109-115
Hauptverfasser:	Tan, J M M, Tock, E P C, Chow, V T K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult amplification Base Sequence Biological and medical sciences breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology C8orf17 Cell Line Cell Transformation, Neoplastic - genetics Chromosomes, Human, Pair 8 - genetics DNA, Complementary - genetics DNA, Neoplasm - genetics EST expressed sequence tag Expressed Sequence Tags Female FISH fluorescence in situ hybridisation G3PDH Gene Expression glyceraldehyde-3-phosphate dehydrogenase Gynecology. Andrology. Obstetrics HPV human papillomavirus Humans Male Mammary gland diseases Medical sciences Molecular Sequence Data MOST-1 Nephrology. Urinary tract diseases normal nucleotides open reading frame Open Reading Frames - genetics ORF Original overexpression PBS PCR phosphate buffered saline polymerase chain reaction Polymerase Chain Reaction - methods prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology RACE rapid amplification of cDNA ends Reverse Transcriptase Polymerase Chain Reaction reverse transcription SDS sodium dodecyl sulfate threshold cycle Tumor Cells, Cultured Tumors Tumors of the urinary system tumour untranslated region Urinary tract. Prostate gland UTR
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