An improved assay technique for uridine diphosphate glucuronosyltransferase activity towards 5-hydroxytryptamine and some properties of the enzyme

A simplified and sensitive procedure for the routine assay of UDP-glucuronosyltransferase activity towards 5-hydroxytryptamine (serotonin) was developed and the reaction product confirmed as the O-glucuronide of this substrate. The assay was used to study some properties of this UDP-glucuronosyltran...

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Veröffentlicht in:	Biochemical journal 1978-12, Vol.175 (3), p.1119-1124
1. Verfasser:	Leakey, J E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cats Diethylnitrosamine - pharmacology Digitonin - pharmacology Glucuronosyltransferase - metabolism In Vitro Techniques Mice Rats Serotonin - metabolism Tissue Distribution Uridine Diphosphate N-Acetylglucosamine - metabolism
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