An optimized approach to membrane capacitance estimation using dual-frequency excitation

We present an optimized solution to the problem of membrane impedance estimation when a patch-clamped cell is stimulated by a dual-frequency, sinusoidal excitation. The complete data set of raw whole-cell current samples is typically reduced, via digital lock-in detection, to measurements of the com...

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Veröffentlicht in:	Biophysical journal 1997-04, Vol.72 (4), p.1641-1658
Hauptverfasser:	Barnett, D.W., Misler, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Medulla - metabolism Animals Catecholamines - secretion Cell Membrane - metabolism Cell Membrane - physiology Chromaffin Cells - metabolism Computer Simulation Electric Conductivity Electric Stimulation Mathematics Patch-Clamp Techniques Rats Software Statistics as Topic
Online-Zugang:	Volltext
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