Association of the Gene Encoding Wingless-Type Mammary Tumor Virus Integration-Site Family Member 5B ( WNT5B) with Type 2 Diabetes

Recent reports have suggested that WNT signaling is an important regulator for adipogenesis or insulin secretion and might be involved in the pathogenesis of type 2 diabetes. To investigate possible roles of the WNT genes in conferring susceptibility to type 2 diabetes, we examined the association o...

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Veröffentlicht in:	American journal of human genetics 2004-11, Vol.75 (5), p.832-843
Hauptverfasser:	Kanazawa, Akio, Tsukada, Syuuichi, Sekine, Akihiro, Tsunoda, Tatsuhiko, Takahashi, Atsushi, Kashiwagi, Atsunori, Tanaka, Yasushi, Babazono, Tetsuya, Matsuda, Masafumi, Kaku, Kohei, Iwamoto, Yasuhiko, Kawamori, Ryuzo, Kikkawa, Ryuichi, Nakamura, Yusuke, Maeda, Shiro
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Adipocytes - metabolism Animals Base Sequence Biological and medical sciences Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance DNA Primers Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Gene Expression Regulation Gene Frequency Genotype Humans Japan Linkage Disequilibrium Liver - metabolism Medical sciences Mice Molecular Sequence Data Multigene Family - genetics Pancreas - metabolism Polymorphism, Single Nucleotide - genetics Proto-Oncogene Proteins - genetics Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA Wnt Proteins
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