Chromosomal Abnormalities among Offspring of Childhood-Cancer Survivors in Denmark: A Population-Based Study

Ionizing radiation and many cancer drugs have the potential to produce germ-cell mutations that might lead to genetic disease in the next generation. In a population-based study, we identified, from records in the Danish Cancer Registry, 4,676 children treated for cancer. Their 6,441 siblings provid...

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Veröffentlicht in:	American journal of human genetics 2004-06, Vol.74 (6), p.1282-1285
Hauptverfasser:	Winther, Jeanette Falck, Boice, John D., Mulvihill, John J., Stovall, Marilyn, Frederiksen, Kirsten, Tawn, E. Janet, Olsen, Jørgen H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Child Child, Preschool Chromosome Aberrations Cohort Studies Denmark Down Syndrome - diagnosis Down Syndrome - epidemiology Down Syndrome - genetics Female Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Genetics, Population Humans Infant Infant, Newborn Karyotyping Male Medical genetics Medical sciences Molecular and cellular biology Neoplasms - mortality Registries Risk Factors Survivors Turner Syndrome - diagnosis Turner Syndrome - epidemiology Turner Syndrome - genetics
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