A Bayesian Joint Model of Multiple Nonlinear Longitudinal and Competing Risks Outcomes for Dynamic Prediction in Multiple Myeloma: Joint Estimation and Corrected Two-Stage Approaches

Predicting cancer-associated clinical events is challenging in oncology. In Multiple Myeloma (MM), a cancer of plasma cells, disease progression is determined by changes in biomarkers, such as serum concentration of the paraprotein secreted by plasma cells (M-protein). Therefore, the time-dependent...

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Veröffentlicht in:Statistics in medicine 2025-02, Vol.44 (3-4), p.e10322
Hauptverfasser: Alvares, Danilo, Barrett, Jessica K, Mercier, François, Roumpanis, Spyros, Yiu, Sean, Castro, Felipe, Schulze, Jochen, Zhu, Yajing
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Sprache:eng
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