Seeking progress in disease modification in Parkinson disease

Disease modification in Parkinson disease (PD) has remained an elusive goal, in spite of large investments over several decades. Following a large meeting of experts, this review article discusses the state of the science, possible reasons for past PD trials’ failures to demonstrate disease-modifyin...

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Veröffentlicht in:	Parkinsonism & related disorders 2021-09, Vol.90, p.134-141
Hauptverfasser:	Lungu, Codrin, Cedarbaum, Jesse M., Dawson, Ted M., Dorsey, E. Ray, Faraco, Carlos, Federoff, Howard J., Fiske, Brian, Fox, Robert, Goldfine, Andrew M., Kieburtz, Karl, Macklin, Eric A., Matthews, Helen, Rafaloff, Gary, Saunders-Pullman, Rachel, Schor, Nina F., Schwarzschild, Michael A., Sieber, Beth-Anne, Simuni, Tanya, Surmeier, Dalton J., Tamiz, Amir, Werner, Milton H., Wright, Clinton B., Wyse, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - analysis Clinical trial Disease modification Drug Discovery Humans National Institute of Neurological Disorders and Stroke (U.S.) Parkinson Parkinson Disease - drug therapy Pharmacotherapy United States
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