Role of miRNAs in Regulating Ascending Aortic Dilation in Bicuspid Aortic Valve Patients Operated for Aortic Stenosis

Deregulation of micro-RNAs (miRNAs) may contribute to mechanisms of injury in the bicuspid aortic valve (BAV). Our objective was to investigate the expression of miRNAs in aortic tissue from patients who underwent aortic valve replacement for aortic stenosis and its relationship with aortic dilatati...

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Veröffentlicht in:	International journal of molecular sciences 2025-01, Vol.26 (2), p.779
Hauptverfasser:	Sanchez-Garcia, Antonio de Jesús, Soule-Egea, Mauricio, Fuentevilla-Alvarez, Giovanny, Vargas-Alarcon, Gilberto, Hernández-Mejia, Benjamín Iván, Martínez-Hernández, Humberto, Mora-Canela, Sergio Luis, Santibanez-Escobar, Felipe, Ávila-Martinez, Valeria, Castrejón-Tellez, Vicente, Alvarez-León, Edith, de la Mora-Cervantes, Regina, Pérez-Torres, Israel, Soto, María Elena
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aorta - metabolism Aorta - pathology Aortic stenosis Aortic Valve - abnormalities Aortic Valve - metabolism Aortic Valve - pathology Aortic Valve - surgery Aortic Valve Stenosis - genetics Aortic Valve Stenosis - metabolism Aortic Valve Stenosis - pathology Aortic Valve Stenosis - surgery Apoptosis Bicuspid Aortic Valve Disease - genetics Bicuspid Aortic Valve Disease - metabolism Bicuspid Aortic Valve Disease - surgery Calcification Calcinosis - genetics Calcinosis - metabolism Calcinosis - pathology Congenital diseases Coronary vessels Dilatation, Pathologic - genetics Disease Female Gene Expression Regulation Growth models Heart Valve Diseases - genetics Heart Valve Diseases - metabolism Heart Valve Diseases - pathology Heart Valve Diseases - surgery Hemodynamics Humans Male Metabolism MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Pathogenesis Shear stress Smooth muscle
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