Echinocandins Pharmacokinetics: A Comprehensive Review of Micafungin, Caspofungin, Anidulafungin, and Rezafungin Population Pharmacokinetic Models and Dose Optimization in Special Populations

In recent years, many population pharmacokinetic (popPK) models have been developed for echinocandins to better understand the pharmacokinetics (PK) of these antifungals. This comprehensive review aimed to summarize popPK models of echinocandins (micafungin, caspofungin, anidulafungin, and rezafungi...

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Veröffentlicht in:	Clinical pharmacokinetics 2025-01, Vol.64 (1), p.27-52
1. Verfasser:	Albanell-Fernández, Marta
Format:	Artikel
Sprache:	eng
Schlagworte:	Anidulafungin - administration & dosage Anidulafungin - pharmacokinetics Antifungal Agents - administration & dosage Antifungal Agents - pharmacokinetics Bibliographic literature Caspofungin - administration & dosage Caspofungin - pharmacokinetics Child Dose-Response Relationship, Drug Drug dosages Echinocandins - administration & dosage Echinocandins - pharmacokinetics Extracorporeal membrane oxygenation Humans Micafungin - administration & dosage Micafungin - pharmacokinetics Microbial Sensitivity Tests Models, Biological Optimization Pediatrics Pharmacokinetics Population Renal replacement therapy Review Therapeutic drug monitoring
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