ATP-sensitive K+ channels and cellular K+ loss in hypoxic and ischaemic mammalian ventricle

1. The contribution of ATP-sensitive K+ (K+ATP) channels to the rapid increase in cellular K+ efflux and shortening of action potential duration (APD) during early myocardial ischaemia and hypoxia remains controversial, because for the first 10 min of ischaemia or hypoxia in intact hearts cytosolic...

Ausführliche Beschreibung