Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer

Stromal cell-derived factor (SDF)-1 (CXC chemokine ligand-12) is a member of the CXC subfamily of chemokines, which, through its cognate receptor (CXC chemokine receptor [CXCR]4), plays an important role in chemotaxis of cancer cells and in tumour metastasis. We conducted the present study to evalua...

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Veröffentlicht in:	Breast cancer research : BCR 2005-01, Vol.7 (4), p.R402-R410, Article R402
Hauptverfasser:	Kang, Hua, Watkins, Gareth, Parr, Christian, Douglas-Jones, Anthony, Mansel, Robert E, Jiang, Wen G
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Breast - cytology Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Cancer cells Care and treatment Cell Movement Chemokine CXCL12 Chemokines, CXC - biosynthesis Chemokines, CXC - genetics Chemokines, CXC - physiology Female Fibroblasts Humans Immunohistochemistry Lymphatic Metastasis Metastasis Neoplasm Invasiveness - physiopathology Patient outcomes Prognosis Reverse Transcriptase Polymerase Chain Reaction RNA Tumor Cells, Cultured
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