Full-component extract of Crithmum maritimum and its effect on epidermal regeneration
As a well-known aromatic herb rich in various bioactive molecules, the extract of is widely used in cosmetics. However, the extraction process for is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other. Thus, the traditional water- or oi...
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| Veröffentlicht in: | RSC advances 2025-01, Vol.15 (3), p.1713-1720 |
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| creator | Huang, Hongbin Qian, Jin Zeng, Lanlan Zhang, Jin Peng, Xiaobo Tang, Xilong Tang, Yanzhang Fu, Meimei Liu, Qi Song, Fengrui Guo, Jinshan Lu, Zhihui |
| description | As a well-known aromatic herb rich in various bioactive molecules, the extract of
is widely used in cosmetics. However, the extraction process for
is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other. Thus, the traditional water- or oil-based extracts of
encompass only water- or oil-soluble components, respectively. The effective components being incomplete results in significantly reduced effects. Therefore, obtaining a full-component extract of
is imperative to ensure its full functionality. Herein, a full-component extract of
based on miscibility between polyol and oil was developed by extracting water-soluble active substances with a ternary solvent, followed by mixing them with oil extracts of
. In ternary solvents, most water-soluble compounds of
can be extracted by ethanol. During evaporation, the water-soluble components are transferred and dissolved in hexanediol from the solvent. Thus, by blending hexanediol with caprylic/capric triglyceride (GTCC), we successfully created a potent full-component extract of
. Through the study of the barrier-weakening 3D full-skin model, it was found that the full-component extract of
, rich in chlorogenic acid, could significantly promote the epidermal regeneration of UV-induced skin damage compared to the oil-based extract components. |
| doi_str_mv | 10.1039/d4ra04301d |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11744354</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3157556617</sourcerecordid><originalsourceid>FETCH-LOGICAL-c183d-d4c3e4e7bf1284f2820d126997a2970af965203d99561bb0c37b7b508a2435273</originalsourceid><addsrcrecordid>eNpVkV1LwzAYhYMobszd-AOklyJU89WPXMnY_IKBIHod0ubtFmmbmbSi_97UzTFzkwM5nPO8eRE6J_iaYCZuNHcKc4aJPkJjinkaU5yK4wM9QlPv33E4aUJoSk7RiImcJRSLMXq77-s6Lm2zsS20XQRfnVNlF9kqmjvTrZu-iRoVlBmUanVkOh9BVcFgaiPYGA2uUXXkYAUtONUZ256hk0rVHqa7exJ67l7nj_Hy-eFpPlvGJcmZjjUvGXDIiorQnFc0p1gHQiEyRUWGVSXSQMm0EElKigKXLCuyIsG5ojzwZ2yCbre5m75oQJdhAqdquXEmMH9Lq4z8_9KatVzZT0lIxkMEDwmXuwRnP3rwnWyML6GuVQu295KRJEuSNCVD2dXWWjrrvYNq30OwHHYhF_xl9ruLRTBfHJLtrX8_z34A8_WEuQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3157556617</pqid></control><display><type>article</type><title>Full-component extract of Crithmum maritimum and its effect on epidermal regeneration</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Huang, Hongbin ; Qian, Jin ; Zeng, Lanlan ; Zhang, Jin ; Peng, Xiaobo ; Tang, Xilong ; Tang, Yanzhang ; Fu, Meimei ; Liu, Qi ; Song, Fengrui ; Guo, Jinshan ; Lu, Zhihui</creator><creatorcontrib>Huang, Hongbin ; Qian, Jin ; Zeng, Lanlan ; Zhang, Jin ; Peng, Xiaobo ; Tang, Xilong ; Tang, Yanzhang ; Fu, Meimei ; Liu, Qi ; Song, Fengrui ; Guo, Jinshan ; Lu, Zhihui</creatorcontrib><description>As a well-known aromatic herb rich in various bioactive molecules, the extract of
is widely used in cosmetics. However, the extraction process for
is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other. Thus, the traditional water- or oil-based extracts of
encompass only water- or oil-soluble components, respectively. The effective components being incomplete results in significantly reduced effects. Therefore, obtaining a full-component extract of
is imperative to ensure its full functionality. Herein, a full-component extract of
based on miscibility between polyol and oil was developed by extracting water-soluble active substances with a ternary solvent, followed by mixing them with oil extracts of
. In ternary solvents, most water-soluble compounds of
can be extracted by ethanol. During evaporation, the water-soluble components are transferred and dissolved in hexanediol from the solvent. Thus, by blending hexanediol with caprylic/capric triglyceride (GTCC), we successfully created a potent full-component extract of
. Through the study of the barrier-weakening 3D full-skin model, it was found that the full-component extract of
, rich in chlorogenic acid, could significantly promote the epidermal regeneration of UV-induced skin damage compared to the oil-based extract components.</description><identifier>ISSN: 2046-2069</identifier><identifier>EISSN: 2046-2069</identifier><identifier>DOI: 10.1039/d4ra04301d</identifier><identifier>PMID: 39835209</identifier><language>eng</language><publisher>England: The Royal Society of Chemistry</publisher><subject>Chemistry</subject><ispartof>RSC advances, 2025-01, Vol.15 (3), p.1713-1720</ispartof><rights>This journal is © The Royal Society of Chemistry.</rights><rights>This journal is © The Royal Society of Chemistry 2025 The Royal Society of Chemistry</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c183d-d4c3e4e7bf1284f2820d126997a2970af965203d99561bb0c37b7b508a2435273</cites><orcidid>0000-0001-7338-8139 ; 0000-0001-8097-4902</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744354/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744354/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39835209$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huang, Hongbin</creatorcontrib><creatorcontrib>Qian, Jin</creatorcontrib><creatorcontrib>Zeng, Lanlan</creatorcontrib><creatorcontrib>Zhang, Jin</creatorcontrib><creatorcontrib>Peng, Xiaobo</creatorcontrib><creatorcontrib>Tang, Xilong</creatorcontrib><creatorcontrib>Tang, Yanzhang</creatorcontrib><creatorcontrib>Fu, Meimei</creatorcontrib><creatorcontrib>Liu, Qi</creatorcontrib><creatorcontrib>Song, Fengrui</creatorcontrib><creatorcontrib>Guo, Jinshan</creatorcontrib><creatorcontrib>Lu, Zhihui</creatorcontrib><title>Full-component extract of Crithmum maritimum and its effect on epidermal regeneration</title><title>RSC advances</title><addtitle>RSC Adv</addtitle><description>As a well-known aromatic herb rich in various bioactive molecules, the extract of
is widely used in cosmetics. However, the extraction process for
is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other. Thus, the traditional water- or oil-based extracts of
encompass only water- or oil-soluble components, respectively. The effective components being incomplete results in significantly reduced effects. Therefore, obtaining a full-component extract of
is imperative to ensure its full functionality. Herein, a full-component extract of
based on miscibility between polyol and oil was developed by extracting water-soluble active substances with a ternary solvent, followed by mixing them with oil extracts of
. In ternary solvents, most water-soluble compounds of
can be extracted by ethanol. During evaporation, the water-soluble components are transferred and dissolved in hexanediol from the solvent. Thus, by blending hexanediol with caprylic/capric triglyceride (GTCC), we successfully created a potent full-component extract of
. Through the study of the barrier-weakening 3D full-skin model, it was found that the full-component extract of
, rich in chlorogenic acid, could significantly promote the epidermal regeneration of UV-induced skin damage compared to the oil-based extract components.</description><subject>Chemistry</subject><issn>2046-2069</issn><issn>2046-2069</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><recordid>eNpVkV1LwzAYhYMobszd-AOklyJU89WPXMnY_IKBIHod0ubtFmmbmbSi_97UzTFzkwM5nPO8eRE6J_iaYCZuNHcKc4aJPkJjinkaU5yK4wM9QlPv33E4aUJoSk7RiImcJRSLMXq77-s6Lm2zsS20XQRfnVNlF9kqmjvTrZu-iRoVlBmUanVkOh9BVcFgaiPYGA2uUXXkYAUtONUZ256hk0rVHqa7exJ67l7nj_Hy-eFpPlvGJcmZjjUvGXDIiorQnFc0p1gHQiEyRUWGVSXSQMm0EElKigKXLCuyIsG5ojzwZ2yCbre5m75oQJdhAqdquXEmMH9Lq4z8_9KatVzZT0lIxkMEDwmXuwRnP3rwnWyML6GuVQu295KRJEuSNCVD2dXWWjrrvYNq30OwHHYhF_xl9ruLRTBfHJLtrX8_z34A8_WEuQ</recordid><startdate>20250116</startdate><enddate>20250116</enddate><creator>Huang, Hongbin</creator><creator>Qian, Jin</creator><creator>Zeng, Lanlan</creator><creator>Zhang, Jin</creator><creator>Peng, Xiaobo</creator><creator>Tang, Xilong</creator><creator>Tang, Yanzhang</creator><creator>Fu, Meimei</creator><creator>Liu, Qi</creator><creator>Song, Fengrui</creator><creator>Guo, Jinshan</creator><creator>Lu, Zhihui</creator><general>The Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7338-8139</orcidid><orcidid>https://orcid.org/0000-0001-8097-4902</orcidid></search><sort><creationdate>20250116</creationdate><title>Full-component extract of Crithmum maritimum and its effect on epidermal regeneration</title><author>Huang, Hongbin ; Qian, Jin ; Zeng, Lanlan ; Zhang, Jin ; Peng, Xiaobo ; Tang, Xilong ; Tang, Yanzhang ; Fu, Meimei ; Liu, Qi ; Song, Fengrui ; Guo, Jinshan ; Lu, Zhihui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c183d-d4c3e4e7bf1284f2820d126997a2970af965203d99561bb0c37b7b508a2435273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>Chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huang, Hongbin</creatorcontrib><creatorcontrib>Qian, Jin</creatorcontrib><creatorcontrib>Zeng, Lanlan</creatorcontrib><creatorcontrib>Zhang, Jin</creatorcontrib><creatorcontrib>Peng, Xiaobo</creatorcontrib><creatorcontrib>Tang, Xilong</creatorcontrib><creatorcontrib>Tang, Yanzhang</creatorcontrib><creatorcontrib>Fu, Meimei</creatorcontrib><creatorcontrib>Liu, Qi</creatorcontrib><creatorcontrib>Song, Fengrui</creatorcontrib><creatorcontrib>Guo, Jinshan</creatorcontrib><creatorcontrib>Lu, Zhihui</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>RSC advances</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huang, Hongbin</au><au>Qian, Jin</au><au>Zeng, Lanlan</au><au>Zhang, Jin</au><au>Peng, Xiaobo</au><au>Tang, Xilong</au><au>Tang, Yanzhang</au><au>Fu, Meimei</au><au>Liu, Qi</au><au>Song, Fengrui</au><au>Guo, Jinshan</au><au>Lu, Zhihui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Full-component extract of Crithmum maritimum and its effect on epidermal regeneration</atitle><jtitle>RSC advances</jtitle><addtitle>RSC Adv</addtitle><date>2025-01-16</date><risdate>2025</risdate><volume>15</volume><issue>3</issue><spage>1713</spage><epage>1720</epage><pages>1713-1720</pages><issn>2046-2069</issn><eissn>2046-2069</eissn><abstract>As a well-known aromatic herb rich in various bioactive molecules, the extract of
is widely used in cosmetics. However, the extraction process for
is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other. Thus, the traditional water- or oil-based extracts of
encompass only water- or oil-soluble components, respectively. The effective components being incomplete results in significantly reduced effects. Therefore, obtaining a full-component extract of
is imperative to ensure its full functionality. Herein, a full-component extract of
based on miscibility between polyol and oil was developed by extracting water-soluble active substances with a ternary solvent, followed by mixing them with oil extracts of
. In ternary solvents, most water-soluble compounds of
can be extracted by ethanol. During evaporation, the water-soluble components are transferred and dissolved in hexanediol from the solvent. Thus, by blending hexanediol with caprylic/capric triglyceride (GTCC), we successfully created a potent full-component extract of
. Through the study of the barrier-weakening 3D full-skin model, it was found that the full-component extract of
, rich in chlorogenic acid, could significantly promote the epidermal regeneration of UV-induced skin damage compared to the oil-based extract components.</abstract><cop>England</cop><pub>The Royal Society of Chemistry</pub><pmid>39835209</pmid><doi>10.1039/d4ra04301d</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-7338-8139</orcidid><orcidid>https://orcid.org/0000-0001-8097-4902</orcidid><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Chemistry |
| title | Full-component extract of Crithmum maritimum and its effect on epidermal regeneration |
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