New Hydrogenated Phenanthrene Glycosides from the Edible Vegetable Elatostema tenuicaudatum W.T.Wang with DPP-IV Inhibitory and Hepatoprotective Activity

Based on molecular networking-guided isolation, 15 previously undescribed hydrogenated phenanthrene glycosides, including eight hexahydro-phenanthrenone glycosides, four tetrahydro-phenanthrenone glycosides, one dihydro-phenanthrenol glycoside, two dimers, and two known dihydrophenanthrene glycoside...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2025-01, Vol.73 (2), p.1273-1292
Hauptverfasser:	Tran Huynh, Quoc-Dung, Hsu, Su-Jung, Duong, Truc-Ly Thi, Liu, Hui-Kang, Liu, Ta-Wei, Chu, Man-Hsiu, Wang, Yun-Han, Nguyen, Dang-Khoa, Phan, Thuy-Tien Thi, Tran, Nguyen-Khanh Huynh, Vo, Thanh-Hoa, Hsi, Hsiao-Yang, Yeh, Tz-Wei, Lee, Ching-Kuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioactive Constituents, Metabolites, and Functions Dipeptidyl Peptidase 4 - chemistry Dipeptidyl Peptidase 4 - metabolism Dipeptidyl-Peptidase IV Inhibitors - chemistry Dipeptidyl-Peptidase IV Inhibitors - pharmacology Glycosides - chemistry Glycosides - pharmacology Hep G2 Cells Humans Liver - drug effects Molecular Docking Simulation Molecular Structure Phenanthrenes - chemistry Phenanthrenes - pharmacology Plant Extracts - chemistry Plant Extracts - pharmacology Protective Agents - chemistry Protective Agents - pharmacology Vegetables - chemistry Vietnam
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