Expression of Caveolin-1 Induces Premature Cellular Senescence in Primary Cultures of Murine Fibroblasts: Stress-Induced Premature Senescence Upregulates the Expression of Endogenous Caveolin-1

Caveolae are vesicular invaginations of the plasma membrane. Caveolin-1 is the principal structural component of caveolae in vivo. Several lines of evidence are consistent with the idea that caveolin-1 functions as a “transformation suppressor” protein. In fact, caveolin-1 mRNA and protein expressio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular biology of the cell 2002-07, Vol.13 (7), p.2502-2517
Hauptverfasser:	Volonte, Daniela, Zhang, Kun, Lisanti, Michael P., Galbiati, Ferruccio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!