Identification and validation of CDK1 as a promising therapeutic target for Eriocitrin in colorectal cancer: a combined bioinformatics and experimental approach

Colorectal cancer (CRC) is a prevalent malignancy worldwide, associated with significant morbidity and mortality. Cyclin-dependent kinase 1 (CDK1) plays a crucial role in cell cycle regulation and has been implicated in various cancers. This study aimed to evaluate the prognostic value of CDK1 in CR...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMC cancer 2025-01, Vol.25 (1), p.76-17, Article 76
Hauptverfasser:	Shen, Jiemiao, Gong, Xing, Ren, Haili, Tang, Xia, Yu, Hairong, Tang, Yilu, Chen, Shen, Ji, Minghui
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cancer Care and treatment CDC2 Protein Kinase - genetics CDC2 Protein Kinase - metabolism Cell Line, Tumor Cell Movement - drug effects Cell Proliferation - drug effects China Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Computational biology Computational Biology - methods Cyclin-dependent kinase 1 Cyclins Development and progression Eriocitrin Gene Expression Regulation, Neoplastic - drug effects Genes Health aspects Humans Molecular docking Molecular Docking Simulation Molecular targeted therapy Mortality Patient outcomes Prognosis Relapse Tumor proteins United States
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!