Targeting KAT7 inhibits the progression of colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related mortality. Epigenetic modifications play a significant role in the progression of CRC. KAT7, a histone acetyltransferase, has an unclear role in CRC. In this research, we analyzed the expression of KAT7 in CRC patients and its correlation...

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Veröffentlicht in:	Theranostics 2025-01, Vol.15 (4), p.1478-1495
Hauptverfasser:	Wang, Hao, Guan, Tianwang, Hu, Rong, Huang, Zhongjie, Liang, Zhao, Lin, Xiaonan, Qiu, Yingqi, Liao, Peiyun, Guo, Xiongbo, Ke, Yushen, Zhang, Honghao, Ou, Caiwen, Li, Yuhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Apoptosis Cell Line, Tumor Cell Movement - genetics Cell Proliferation Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Disease Progression Female Gene Expression Regulation, Neoplastic Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Histones - metabolism Humans Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Lung Neoplasms - secondary Mice Mice, Inbred BALB C Mice, Nude Prognosis Research Paper Signal Transduction
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