The effect of N-acylglucosamines on the biosynthesis and secretion of insulin in the rat

The effects of N-acylglucosamines on insulin release have been studied. N-Acylglucosamines stimulated insulin release from rat islets in vitro only if a sub-stimulatory concentration of glucose was also present, and this secretory response was abolished by mannoheptulose. In perifused islets the rap...

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Veröffentlicht in:	Biochemical journal 1976-03, Vol.154 (3), p.701-707
Hauptverfasser:	Ashcroft, S J, Crossley, J R, Crossley, P C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylglucosamine - pharmacology Animals Glucosamine - analogs & derivatives Glucose - pharmacology In Vitro Techniques Insulin - biosynthesis Insulin - metabolism Insulin Secretion Islets of Langerhans - metabolism Male Mannoheptulose - pharmacology Rats
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