Long non-coding RNA NEAT1 promotes ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis

Granulosa cell proliferation and survival are essential for normal ovarian function and follicular development. Long non-coding RNAs (lncRNAs) have emerged as important regulators of cell proliferation and differentiation. Nuclear paraspeckle assembly transcript 1 (NEAT1) has been implicated in vari...

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Veröffentlicht in:	Journal of ovarian research 2025-01, Vol.18 (1), p.6-10, Article 6
Hauptverfasser:	He, Lina, Lin, Jie, Qin, Zhengwen, Xu, Qing, Hao, Li, Fu, Yanhong, Ran, Xu, Chen, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cell cycle Cell Cycle - genetics Cell differentiation Cell Line, Tumor Cell Proliferation - genetics Female Granulosa cells Granulosa Cells - metabolism Humans IGF1 Insulin-Like Growth Factor I - genetics Insulin-Like Growth Factor I - metabolism Long non-coding RNA Luciferase MicroRNAs - genetics MicroRNAs - metabolism miR-29a-3p NEAT1 Physiological aspects RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Stein-Leventhal syndrome
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