Efficacy and Satisfaction of a Chemically Characterized Malva sylvestris L. Extract-Based Food Supplement for Functional Constipation in Healthy Consumers: Preliminary Results of a Questionnaire-Based Survey

L. is rich in mucilage and is traditionally used for the management of numerous ailments including gastrointestinal disorders. Functional constipation (FC) is a gastrointestinal condition characterized by defecation anomalies such as infrequent stools, difficulty in stool passage, or both in the abs...

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Veröffentlicht in:Nutrients 2025-01, Vol.17 (1), p.77
Hauptverfasser: Lellis, Lorenza Francesca De, Ullah, Hammad, Morone, Maria Vittoria, Buccato, Daniele Giuseppe, Baldi, Alessandra, Minno, Alessandro Di, Larsen, Danaé S, Sacchi, Roberto, Daglia, Maria
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creator Lellis, Lorenza Francesca De
Ullah, Hammad
Morone, Maria Vittoria
Buccato, Daniele Giuseppe
Baldi, Alessandra
Minno, Alessandro Di
Larsen, Danaé S
Sacchi, Roberto
Daglia, Maria
description L. is rich in mucilage and is traditionally used for the management of numerous ailments including gastrointestinal disorders. Functional constipation (FC) is a gastrointestinal condition characterized by defecation anomalies such as infrequent stools, difficulty in stool passage, or both in the absence of pathological abnormalities. FC can be reduced through lifestyle factors and dietary intervention. This consumer-based survey aimed to assess the efficacy of a extract-based food supplement on the improvement of FC. Healthy participants ( = 56), enrolled in a consumer-based survey, took a food supplement containing a chemically characterized extract at a dose of 20 mL/day (containing 750 mg of extract rich in food fiber and polyphenols) for 20 days on the advice of their pharmacist. The study evaluated bowel movement frequency (intestinal diary), stool consistency (Bristol Stool Form Scale, BSFS), and abdominal pain (Visual Analogue Scale, VAS), at baseline (T0), after 10 days (T1), and after 20 days (T2). A significant increase in bowel movement frequency and stool consistency ( < 0.001) with a significant decrease in abdominal pain ( < 0.001) was observed. Additionally, this food supplement was well-tolerated as no adverse effects were reported by the enrolled subjects. -based food supplement showed promising effectiveness and satisfaction in improving FC in healthy subjects, however, randomized clinical studies are needed to confirm these preliminary results.
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subjects Abdominal Pain - drug therapy
Adult
Amino acids
Constipation
Constipation - drug therapy
Consumer behavior
Defecation - drug effects
Dietary Fiber
Dietary Supplements
Female
Food
Glucose
Healthy Volunteers
Humans
Laxatives
Life sciences
Male
Malva
Middle Aged
Patient Satisfaction
Plant Extracts - pharmacology
Polyphenols
Proteins
Quality of life
Questionnaires
Surveys and Questionnaires
Treatment Outcome
Young Adult
title Efficacy and Satisfaction of a Chemically Characterized Malva sylvestris L. Extract-Based Food Supplement for Functional Constipation in Healthy Consumers: Preliminary Results of a Questionnaire-Based Survey
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