Folic Acid and Methyltetrahydrofolate Supplementation in the Mthfr677C>T Mouse Model with Hepatic Steatosis

Background/Objectives: The MTHFR677C>T gene variant results in a thermolabile MTHFR enzyme associated with elevated plasma homocysteine in TT individuals. Health risks associated with the TT genotype may be modified by dietary and supplemental folate intake. Supplementation with methyltetrahydrof...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nutrients 2024-12, Vol.17 (1), p.82
Hauptverfasser:	Christensen, Karen E., Faquette, Marie-Lou, Leclerc, Daniel, Keser, Vafa, Luan, Yan, Bennett-Firmin, Jeanna L., Malysheva, Olga V., Reagan, Alaina M., Howell, Gareth R., Caudill, Marie A., Bottiglieri, Teodoro, Rozen, Rima
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Diet Dihydrofolate reductase Enzymes Females Homocysteine Lipids Liver Metabolism Metabolites Plasma Vitamin B
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!