Generalizability of Alzheimer’s disease plasma biomarkers phospho‐Tau and beta amyloid in individuals of diverse genetic ancestries

Background Plasma concentrations of phosphorylated threonine‐181 of Tau (pTau181) and the ratio of amyloid beta isoforms Aβ42/Aβ40 are biomarkers for differential diagnosis and preclinical detection of Alzheimer disease (AD). However, assessment of the utility of these biomarkers has been in non‐His...

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Veröffentlicht in:Alzheimer's & dementia 2024-12, Vol.20 (S2), p.n/a
Hauptverfasser: Griswold, Anthony J., Rajabli, Farid, Gu, Tianjie, Arvizu, Jamie, Golightly, Charles G., Whitehead, Patrice L., Hamilton‐Nelson, Kara L., Adams, Larry D., Celis, Katrina, Sanchez, Jose Javier, Mena, Pedro R., Starks, Takiyah D., Illanes‐Manrique, Maryenela Z., Silva‐Vergara, Concepcion, Cuccaro, Michael L., Vance, Jeffery M., Feliciano‐Astacio, Briseida E., Cornejo‐Olivas, Mario, Byrd, Goldie S., Beecham, Gary, Haines, Jonathan L., Pericak‐Vance, Margaret A
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Sprache:eng
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