Cohabitation of insulators and silencing elements in yeast subtelomeric regions

In budding yeast, the telomeric DNA is flanked by a combination of two subtelomeric repetitive sequences, the X and Y′ elements. We have investigated the influence of these sequences on telomeric silencing. The telomere‐proximal portion of either X or Y′ dampened silencing when located between the t...

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Veröffentlicht in:	The EMBO journal 1999-05, Vol.18 (9), p.2522-2537
Hauptverfasser:	Fourel, G, Revardel, E, Koering, C.E, Gilson, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Centromere chromatin chromosomes Chromosomes, Fungal Cohabitation DNA-Binding Proteins - metabolism Fungal Proteins - metabolism gene expression Gene Expression Regulation, Fungal genetic regulation hml locus insulator loci Models, Genetic Protein Binding REB1 repetitive sequences Repetitive Sequences, Nucleic Acid reporter genes Reproduction - genetics Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins silencer Silent Information Regulator Proteins, Saccharomyces cerevisiae subtelomeric anti-silencing regions subtelomeric core x element subtelomeric repetitive sequences subtelomeric y element TBF1 Telomere telomeres Trans-Activators - metabolism Transcription Factors ura3 gene Yeasts
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