Novel Isoforms of Adhesion G Protein-Coupled Receptor B1 (ADGRB1/BAI1) Generated from an Alternative Promoter in Intron 17

Brain-specific angiogenesis inhibitor 1 (BAI1) belongs to the adhesion G-protein-coupled receptors, which exhibit large multi-domain extracellular N termini that mediate cell–cell and cell–matrix interactions. To explore the existence of BAI1 isoforms, we queried genomic datasets for markers of acti...

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Veröffentlicht in:	Molecular neurobiology 2025-01, Vol.62 (1), p.900-917
Hauptverfasser:	Parag, Rashed Rezwan, Yamamoto, Takahiro, Saito, Kiyotaka, Zhu, Dan, Yang, Liquan, Van Meir, Erwin G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - genetics Amino acids Angiogenesis inhibitors Angiogenic Proteins - genetics Angiogenic Proteins - metabolism Animals Biomedical and Life Sciences Biomedicine Brain - metabolism Cell Biology Chromatin Codons Exons Exons - genetics G protein-coupled receptors Humans Introns - genetics Isoforms Mice Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neurobiology Neurology Neurosciences Promoter Regions, Genetic - genetics Protein Isoforms - genetics Protein Isoforms - metabolism Proteins Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Reverse transcription RNA, Messenger - genetics RNA, Messenger - metabolism
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