Expression of human tau in adult Drosophila melanogaster causes a sexually dimorphic sleep phenotype

Background Alzheimer’s disease (AD) is the primary cause of dementia, characterized by early amyloid beta accumulation, subsequent tau pathology, and eventually synaptic and neuronal loss. Sleep disturbances, a clinical phenotype in AD, are linked to amyloid beta and impaired protein clearance. Howe...

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Veröffentlicht in:	Alzheimer's & dementia 2024-12, Vol.20 (S1), p.n/a
Hauptverfasser:	Mouofo, Edmond N, Catterson, James, Verstreken, Patrik, Spires‐Jones, Tara L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Science and Pathogenesis
Online-Zugang:	Volltext
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