Genome‐wide Interaction and Stratified Study with Smoking Identifies Association of APAF1 and MIXL1/LIN9 with Alzheimer’s Disease

Background Alzheimer’s disease (AD) has both genetic and environmental risk factors. Gene‐environment interaction may help explain some missing heritability. There is strong evidence for cigarette smoking as a risk factor for AD. To identify genetic‐smoking‐related associations with AD, we conducted...

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Veröffentlicht in:Alzheimer's & dementia 2024-12, Vol.20 (S1), p.n/a
Hauptverfasser: Dacey, Ryan, Han, Xudong, Moore, Mackenzie R, Chung, Jaeyoon, Durape, Shruti, Rosenthaler, Max, Uretsky, Madeline, Abdolmohammadi, Bobak, Lee, Annie J., Brickman, Adam M., Hohman, Timothy J., Cuccaro, Michael L., Bennett, David A., Crane, Paul K., Kamboh, M. Ilyas, Kukull, Walter A., Au, Rhoda, Haines, Jonathan L., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Mayeux, Richard, Lunetta, Kathryn L., Farrer, Lindsay A., Mez, Jesse
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Sprache:eng
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