Genes that escape X chromosome inactivation are associated with Alzheimer’s disease endophenotypes: findings from ROSMAP

Background Women are disproportionately affected by Alzheimer’s disease (AD) and exhibit greater AD neuropathology than men. Women possess two X chromosomes, with one randomly silenced across each cell for dosage compensation. X chromosome inactivation (XCI) is not complete, and XCI‐escaping genes p...

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Veröffentlicht in:	Alzheimer's & dementia 2024-12, Vol.20 (S1), p.n/a
Hauptverfasser:	Seto, Mabel, Clifton, Michelle, Coughlan, Gillian T, Boyle, Rory, Birkenbihl, Colin, Wang, Ting‐Chen, De Jager, Philip L., Schneider, Julie A., Sperling, Reisa A, Wang, Yanling, Bennett, David A., Hohman, Timothy J., Yang, Hyun‐Sik, Dumitrescu, Logan C., Buckley, Rachel F
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Science and Pathogenesis
Online-Zugang:	Volltext
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