Cross‐Ancestry Meta‐Analysis of APOE‐ε4 Stratified GWAS of Longitudinal Cognitive Decline in Older Adults

Background The Apolipoprotein E ε4 (APOE‐ε4) allele is common in the population, but acts as the strongest genetic risk factor for late‐onset Alzheimer’s disease (AD). Despite the strength of the association, there is notable heterogeneity in the population including a strong modifying effect of gen...

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Veröffentlicht in:	Alzheimer's & dementia 2024-12, Vol.20 (S1), p.n/a
Hauptverfasser:	Contreras, Alex G., Walters, Skylar, Eissman, Jaclyn M., Archer, Derek B., Regelson, Alexandra N., Durant, Alaina, Mukherjee, Shubhabrata, Lee, Michael L., Choi, Seo‐Eun, Scollard, Phoebe, Trittschuh, Emily H., Mez, Jesse, Bush, William S., Kunkle, Brian W., Naj, Adam C., Gifford, Katherine A., Bilgel, Murat, Kuzma, Amanda B, Cuccaro, Michael L., Cruchaga, Carlos, Pericak‐Vance, Margaret A, Farrer, Lindsay A., Wang, Li‐San, Schellenberg, Gerard D., Mayeux, Richard, Haines, Jonathan L., Jefferson, Angela L., Kukull, Walter A., Keene, C. Dirk, Saykin, Andrew J., Thompson, Paul M., Martin, Eden R., Albert, Marilyn S., Johnson, Sterling C., Engelman, Corinne D., Ferrucci, Luigi, Bennett, David A., Barnes, Lisa L., Schneider, Julie A., Resnick, Susan M., Sperling, Reisa A, Crane, Paul K., Dumitrescu, Logan C., Hohman, Timothy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Science and Pathogenesis
Online-Zugang:	Volltext
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