A specific 3′ exonuclease activity of UvrABC

Specific cutting of undamaged DNA by UvrABC nuclease is observed. It occurs seven nucleotides (nt) from the 3′ terminus of oligonucleotides annealed to single‐stranded M13 DNA circles. Although the location of the UvrABC cut on undamaged DNA is similar to that of the cut on the 5′ side of a damaged...

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Veröffentlicht in:	The EMBO journal 1998-01, Vol.17 (2), p.626-633
Hauptverfasser:	Gordienko, Irina, Rupp, W.Dean
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism DNA Damage DNA Helicases DNA Repair DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Endodeoxyribonucleases Enzyme Activation - genetics Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli Proteins Exonucleases - metabolism RecA-mediated exchanges SOS response UvrABC 3′ exonuclease UvrABC 5′ side cut
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