Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

Prolactin (PRL) has been implicated in numerous physiological and developmental processes. The mouse PRL gene was disrupted by homologous recombination. The mutation caused infertility in female mice, but did not prevent female mice from manifesting spontaneous maternal behaviors. PRL‐deficient male...

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Veröffentlicht in:The EMBO journal 1997-12, Vol.16 (23), p.6926-6935
Hauptverfasser: Horseman, Nelson D., Zhao, Wenzhu, Montecino-Rodriguez, Encarnacion, Tanaka, Minoru, Nakashima, Kunio, Engle, Sandra J., Smith, Frost, Markoff, Edith, Dorshkind, Kenneth
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Sprache:eng
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