Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?

The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms. Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid...

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Veröffentlicht in:Brain and behavior 2025-01, Vol.15 (1), p.e70234
Hauptverfasser: Song, Yunfei, Song, Guoqiang, Liu, Guijing, Mao, Limei, An, Xiuhu, Peng, Chao, Li, Jian, Chen, Yan, Li, Hongwen, Hou, Changkai, Wang, Bangyue, Zhao, Yan, Wang, Xiangdong, Yin, Gangfeng, Yang, Xinyu
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container_issue 1
container_start_page e70234
container_title Brain and behavior
container_volume 15
creator Song, Yunfei
Song, Guoqiang
Liu, Guijing
Mao, Limei
An, Xiuhu
Peng, Chao
Li, Jian
Chen, Yan
Li, Hongwen
Hou, Changkai
Wang, Bangyue
Zhao, Yan
Wang, Xiangdong
Yin, Gangfeng
Yang, Xinyu
description The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms. Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid hemorrhage, specifically those who presented with Mirror Aneurysms upon admission to our institutions. According to the different endovascular treatment stages, these patients were grouped into the multistage cohort and the single-stage cohort. A total of 216 aneurysms were identified among the 108 patients, with every patient having one ruptured aneurysm. The duration of follow-up was 2 years in both groups. In the single-stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2-year follow-up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. Five complications were encountered, including cerebral vasospasm in three patients, cerebral hemorrhage in one patient, and thromboembolism in one patient. In the multistage cohort, only the ruptured aneurysm (amounting to 51 in total) received treatment at the initial occurrence, while the remaining 51 aneurysms were addressed subsequently. Throughout the 2-year follow-up period, 46 subjects exhibited a modified Rankin scale score ≤2. Overall, four complications were documented, including cerebral vasospasm in two patients, a subarachnoid hemorrhage in one patient, and thromboembolism in one patient. The safety and effectiveness of both endovascular treatment groups have been verified for patients with Mirror Aneurysms suffering from subarachnoid hemorrhage. If feasible, single-stage embolization should be considered a viable treatment option for these patients.
doi_str_mv 10.1002/brb3.70234
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Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid hemorrhage, specifically those who presented with Mirror Aneurysms upon admission to our institutions. According to the different endovascular treatment stages, these patients were grouped into the multistage cohort and the single-stage cohort. A total of 216 aneurysms were identified among the 108 patients, with every patient having one ruptured aneurysm. The duration of follow-up was 2 years in both groups. In the single-stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2-year follow-up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. Five complications were encountered, including cerebral vasospasm in three patients, cerebral hemorrhage in one patient, and thromboembolism in one patient. In the multistage cohort, only the ruptured aneurysm (amounting to 51 in total) received treatment at the initial occurrence, while the remaining 51 aneurysms were addressed subsequently. Throughout the 2-year follow-up period, 46 subjects exhibited a modified Rankin scale score ≤2. Overall, four complications were documented, including cerebral vasospasm in two patients, a subarachnoid hemorrhage in one patient, and thromboembolism in one patient. The safety and effectiveness of both endovascular treatment groups have been verified for patients with Mirror Aneurysms suffering from subarachnoid hemorrhage. If feasible, single-stage embolization should be considered a viable treatment option for these patients.</description><identifier>ISSN: 2162-3279</identifier><identifier>EISSN: 2162-3279</identifier><identifier>DOI: 10.1002/brb3.70234</identifier><identifier>PMID: 39740791</identifier><language>eng</language><publisher>United States: John Wiley and Sons Inc</publisher><subject>Adult ; Aged ; Aneurysm, Ruptured - complications ; Aneurysm, Ruptured - diagnostic imaging ; Aneurysm, Ruptured - therapy ; Embolization, Therapeutic - methods ; Endovascular Procedures - methods ; Female ; Follow-Up Studies ; Humans ; Intracranial Aneurysm - complications ; Intracranial Aneurysm - diagnostic imaging ; Intracranial Aneurysm - therapy ; Male ; Middle Aged ; Original ; Prospective Studies ; Subarachnoid Hemorrhage - complications ; Subarachnoid Hemorrhage - diagnostic imaging ; Subarachnoid Hemorrhage - therapy ; Treatment Outcome</subject><ispartof>Brain and behavior, 2025-01, Vol.15 (1), p.e70234</ispartof><rights>2024 The Author(s). Brain and Behavior published by Wiley Periodicals LLC.</rights><rights>2024 The Author(s). published by Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1474-3547deba141376d1236b93f8a2a8ca8f66c87a9194c38903c0c76911e7f1628a3</cites><orcidid>0009-0004-4678-5023</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688114/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688114/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39740791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Song, Yunfei</creatorcontrib><creatorcontrib>Song, Guoqiang</creatorcontrib><creatorcontrib>Liu, Guijing</creatorcontrib><creatorcontrib>Mao, Limei</creatorcontrib><creatorcontrib>An, Xiuhu</creatorcontrib><creatorcontrib>Peng, Chao</creatorcontrib><creatorcontrib>Li, Jian</creatorcontrib><creatorcontrib>Chen, Yan</creatorcontrib><creatorcontrib>Li, Hongwen</creatorcontrib><creatorcontrib>Hou, Changkai</creatorcontrib><creatorcontrib>Wang, Bangyue</creatorcontrib><creatorcontrib>Zhao, Yan</creatorcontrib><creatorcontrib>Wang, Xiangdong</creatorcontrib><creatorcontrib>Yin, Gangfeng</creatorcontrib><creatorcontrib>Yang, Xinyu</creatorcontrib><title>Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?</title><title>Brain and behavior</title><addtitle>Brain Behav</addtitle><description>The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms. 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subjects Adult
Aged
Aneurysm, Ruptured - complications
Aneurysm, Ruptured - diagnostic imaging
Aneurysm, Ruptured - therapy
Embolization, Therapeutic - methods
Endovascular Procedures - methods
Female
Follow-Up Studies
Humans
Intracranial Aneurysm - complications
Intracranial Aneurysm - diagnostic imaging
Intracranial Aneurysm - therapy
Male
Middle Aged
Original
Prospective Studies
Subarachnoid Hemorrhage - complications
Subarachnoid Hemorrhage - diagnostic imaging
Subarachnoid Hemorrhage - therapy
Treatment Outcome
title Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?
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