Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?
The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms. Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid...
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creator | Song, Yunfei Song, Guoqiang Liu, Guijing Mao, Limei An, Xiuhu Peng, Chao Li, Jian Chen, Yan Li, Hongwen Hou, Changkai Wang, Bangyue Zhao, Yan Wang, Xiangdong Yin, Gangfeng Yang, Xinyu |
description | The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms.
Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid hemorrhage, specifically those who presented with Mirror Aneurysms upon admission to our institutions. According to the different endovascular treatment stages, these patients were grouped into the multistage cohort and the single-stage cohort.
A total of 216 aneurysms were identified among the 108 patients, with every patient having one ruptured aneurysm. The duration of follow-up was 2 years in both groups. In the single-stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2-year follow-up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. Five complications were encountered, including cerebral vasospasm in three patients, cerebral hemorrhage in one patient, and thromboembolism in one patient. In the multistage cohort, only the ruptured aneurysm (amounting to 51 in total) received treatment at the initial occurrence, while the remaining 51 aneurysms were addressed subsequently. Throughout the 2-year follow-up period, 46 subjects exhibited a modified Rankin scale score ≤2. Overall, four complications were documented, including cerebral vasospasm in two patients, a subarachnoid hemorrhage in one patient, and thromboembolism in one patient.
The safety and effectiveness of both endovascular treatment groups have been verified for patients with Mirror Aneurysms suffering from subarachnoid hemorrhage. If feasible, single-stage embolization should be considered a viable treatment option for these patients. |
doi_str_mv | 10.1002/brb3.70234 |
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Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid hemorrhage, specifically those who presented with Mirror Aneurysms upon admission to our institutions. According to the different endovascular treatment stages, these patients were grouped into the multistage cohort and the single-stage cohort.
A total of 216 aneurysms were identified among the 108 patients, with every patient having one ruptured aneurysm. The duration of follow-up was 2 years in both groups. In the single-stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2-year follow-up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. Five complications were encountered, including cerebral vasospasm in three patients, cerebral hemorrhage in one patient, and thromboembolism in one patient. In the multistage cohort, only the ruptured aneurysm (amounting to 51 in total) received treatment at the initial occurrence, while the remaining 51 aneurysms were addressed subsequently. Throughout the 2-year follow-up period, 46 subjects exhibited a modified Rankin scale score ≤2. Overall, four complications were documented, including cerebral vasospasm in two patients, a subarachnoid hemorrhage in one patient, and thromboembolism in one patient.
The safety and effectiveness of both endovascular treatment groups have been verified for patients with Mirror Aneurysms suffering from subarachnoid hemorrhage. If feasible, single-stage embolization should be considered a viable treatment option for these patients.</description><identifier>ISSN: 2162-3279</identifier><identifier>EISSN: 2162-3279</identifier><identifier>DOI: 10.1002/brb3.70234</identifier><identifier>PMID: 39740791</identifier><language>eng</language><publisher>United States: John Wiley and Sons Inc</publisher><subject>Adult ; Aged ; Aneurysm, Ruptured - complications ; Aneurysm, Ruptured - diagnostic imaging ; Aneurysm, Ruptured - therapy ; Embolization, Therapeutic - methods ; Endovascular Procedures - methods ; Female ; Follow-Up Studies ; Humans ; Intracranial Aneurysm - complications ; Intracranial Aneurysm - diagnostic imaging ; Intracranial Aneurysm - therapy ; Male ; Middle Aged ; Original ; Prospective Studies ; Subarachnoid Hemorrhage - complications ; Subarachnoid Hemorrhage - diagnostic imaging ; Subarachnoid Hemorrhage - therapy ; Treatment Outcome</subject><ispartof>Brain and behavior, 2025-01, Vol.15 (1), p.e70234</ispartof><rights>2024 The Author(s). Brain and Behavior published by Wiley Periodicals LLC.</rights><rights>2024 The Author(s). published by Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1474-3547deba141376d1236b93f8a2a8ca8f66c87a9194c38903c0c76911e7f1628a3</cites><orcidid>0009-0004-4678-5023</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688114/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688114/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39740791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Song, Yunfei</creatorcontrib><creatorcontrib>Song, Guoqiang</creatorcontrib><creatorcontrib>Liu, Guijing</creatorcontrib><creatorcontrib>Mao, Limei</creatorcontrib><creatorcontrib>An, Xiuhu</creatorcontrib><creatorcontrib>Peng, Chao</creatorcontrib><creatorcontrib>Li, Jian</creatorcontrib><creatorcontrib>Chen, Yan</creatorcontrib><creatorcontrib>Li, Hongwen</creatorcontrib><creatorcontrib>Hou, Changkai</creatorcontrib><creatorcontrib>Wang, Bangyue</creatorcontrib><creatorcontrib>Zhao, Yan</creatorcontrib><creatorcontrib>Wang, Xiangdong</creatorcontrib><creatorcontrib>Yin, Gangfeng</creatorcontrib><creatorcontrib>Yang, Xinyu</creatorcontrib><title>Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?</title><title>Brain and behavior</title><addtitle>Brain Behav</addtitle><description>The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms.
Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid hemorrhage, specifically those who presented with Mirror Aneurysms upon admission to our institutions. According to the different endovascular treatment stages, these patients were grouped into the multistage cohort and the single-stage cohort.
A total of 216 aneurysms were identified among the 108 patients, with every patient having one ruptured aneurysm. The duration of follow-up was 2 years in both groups. In the single-stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2-year follow-up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. Five complications were encountered, including cerebral vasospasm in three patients, cerebral hemorrhage in one patient, and thromboembolism in one patient. In the multistage cohort, only the ruptured aneurysm (amounting to 51 in total) received treatment at the initial occurrence, while the remaining 51 aneurysms were addressed subsequently. Throughout the 2-year follow-up period, 46 subjects exhibited a modified Rankin scale score ≤2. Overall, four complications were documented, including cerebral vasospasm in two patients, a subarachnoid hemorrhage in one patient, and thromboembolism in one patient.
The safety and effectiveness of both endovascular treatment groups have been verified for patients with Mirror Aneurysms suffering from subarachnoid hemorrhage. If feasible, single-stage embolization should be considered a viable treatment option for these patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Aneurysm, Ruptured - complications</subject><subject>Aneurysm, Ruptured - diagnostic imaging</subject><subject>Aneurysm, Ruptured - therapy</subject><subject>Embolization, Therapeutic - methods</subject><subject>Endovascular Procedures - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Intracranial Aneurysm - complications</subject><subject>Intracranial Aneurysm - diagnostic imaging</subject><subject>Intracranial Aneurysm - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original</subject><subject>Prospective Studies</subject><subject>Subarachnoid Hemorrhage - complications</subject><subject>Subarachnoid Hemorrhage - diagnostic imaging</subject><subject>Subarachnoid Hemorrhage - therapy</subject><subject>Treatment Outcome</subject><issn>2162-3279</issn><issn>2162-3279</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU9LxDAQxYMorqxe_ACSowirmSTbtF5EZP0DisLqOUzTdDfSNmvSCn57s66K5pLw8ps3MzxCDoGdAmP8rAylOFWMC7lF9jhkfCK4Krb_vEfkIMZXls4UJJdsl4xEoSRTBewRP-sq_47RDA0G-hws9q3teupr-uBC8IFednYIH7GN1HV0PpQY0Cw77yp6a1sfwhIXlj5h71JZPKdz1y0aS-f9Wk7lD0PTu9WPcrFPdmpsoj34vsfk5Xr2fHU7uX-8ubu6vJ8YkEpOxFSqypYIEoTKKuAiKwtR58gxN5jXWWZyhQUU0oi8YMIwo7ICwKo6rZ2jGJOLje9qKFtbmTRcwEavgmsxfGiPTv__6dxSL_y7BsjyHEAmh-Nvh-DfBht73bpobNNgZ_0QtYApm3KR8ISebFATfIzB1r99gOl1Snqdkv5KKcFHfyf7RX8yEZ8yqI4z</recordid><startdate>202501</startdate><enddate>202501</enddate><creator>Song, Yunfei</creator><creator>Song, Guoqiang</creator><creator>Liu, Guijing</creator><creator>Mao, Limei</creator><creator>An, Xiuhu</creator><creator>Peng, Chao</creator><creator>Li, Jian</creator><creator>Chen, Yan</creator><creator>Li, Hongwen</creator><creator>Hou, Changkai</creator><creator>Wang, Bangyue</creator><creator>Zhao, Yan</creator><creator>Wang, Xiangdong</creator><creator>Yin, Gangfeng</creator><creator>Yang, Xinyu</creator><general>John Wiley and Sons Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0009-0004-4678-5023</orcidid></search><sort><creationdate>202501</creationdate><title>Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?</title><author>Song, Yunfei ; Song, Guoqiang ; Liu, Guijing ; Mao, Limei ; An, Xiuhu ; Peng, Chao ; Li, Jian ; Chen, Yan ; Li, Hongwen ; Hou, Changkai ; Wang, Bangyue ; Zhao, Yan ; Wang, Xiangdong ; Yin, Gangfeng ; Yang, Xinyu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1474-3547deba141376d1236b93f8a2a8ca8f66c87a9194c38903c0c76911e7f1628a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aneurysm, Ruptured - complications</topic><topic>Aneurysm, Ruptured - diagnostic imaging</topic><topic>Aneurysm, Ruptured - therapy</topic><topic>Embolization, Therapeutic - methods</topic><topic>Endovascular Procedures - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Intracranial Aneurysm - complications</topic><topic>Intracranial Aneurysm - diagnostic imaging</topic><topic>Intracranial Aneurysm - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original</topic><topic>Prospective Studies</topic><topic>Subarachnoid Hemorrhage - complications</topic><topic>Subarachnoid Hemorrhage - diagnostic imaging</topic><topic>Subarachnoid Hemorrhage - therapy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Song, Yunfei</creatorcontrib><creatorcontrib>Song, Guoqiang</creatorcontrib><creatorcontrib>Liu, Guijing</creatorcontrib><creatorcontrib>Mao, Limei</creatorcontrib><creatorcontrib>An, Xiuhu</creatorcontrib><creatorcontrib>Peng, Chao</creatorcontrib><creatorcontrib>Li, Jian</creatorcontrib><creatorcontrib>Chen, Yan</creatorcontrib><creatorcontrib>Li, Hongwen</creatorcontrib><creatorcontrib>Hou, Changkai</creatorcontrib><creatorcontrib>Wang, Bangyue</creatorcontrib><creatorcontrib>Zhao, Yan</creatorcontrib><creatorcontrib>Wang, Xiangdong</creatorcontrib><creatorcontrib>Yin, Gangfeng</creatorcontrib><creatorcontrib>Yang, Xinyu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Brain and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Song, Yunfei</au><au>Song, Guoqiang</au><au>Liu, Guijing</au><au>Mao, Limei</au><au>An, Xiuhu</au><au>Peng, Chao</au><au>Li, Jian</au><au>Chen, Yan</au><au>Li, Hongwen</au><au>Hou, Changkai</au><au>Wang, Bangyue</au><au>Zhao, Yan</au><au>Wang, Xiangdong</au><au>Yin, Gangfeng</au><au>Yang, Xinyu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?</atitle><jtitle>Brain and behavior</jtitle><addtitle>Brain Behav</addtitle><date>2025-01</date><risdate>2025</risdate><volume>15</volume><issue>1</issue><spage>e70234</spage><pages>e70234-</pages><issn>2162-3279</issn><eissn>2162-3279</eissn><abstract>The study evaluated the effectiveness and safety of single-stage versus multistage endovascular treatment in subarachnoid hemorrhage patients with Mirror Aneurysms.
Our research team performed a prospective study, focusing on the radiographic and clinical data of patients diagnosed with subarachnoid hemorrhage, specifically those who presented with Mirror Aneurysms upon admission to our institutions. According to the different endovascular treatment stages, these patients were grouped into the multistage cohort and the single-stage cohort.
A total of 216 aneurysms were identified among the 108 patients, with every patient having one ruptured aneurysm. The duration of follow-up was 2 years in both groups. In the single-stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2-year follow-up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. Five complications were encountered, including cerebral vasospasm in three patients, cerebral hemorrhage in one patient, and thromboembolism in one patient. In the multistage cohort, only the ruptured aneurysm (amounting to 51 in total) received treatment at the initial occurrence, while the remaining 51 aneurysms were addressed subsequently. Throughout the 2-year follow-up period, 46 subjects exhibited a modified Rankin scale score ≤2. Overall, four complications were documented, including cerebral vasospasm in two patients, a subarachnoid hemorrhage in one patient, and thromboembolism in one patient.
The safety and effectiveness of both endovascular treatment groups have been verified for patients with Mirror Aneurysms suffering from subarachnoid hemorrhage. If feasible, single-stage embolization should be considered a viable treatment option for these patients.</abstract><cop>United States</cop><pub>John Wiley and Sons Inc</pub><pmid>39740791</pmid><doi>10.1002/brb3.70234</doi><orcidid>https://orcid.org/0009-0004-4678-5023</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aneurysm, Ruptured - complications Aneurysm, Ruptured - diagnostic imaging Aneurysm, Ruptured - therapy Embolization, Therapeutic - methods Endovascular Procedures - methods Female Follow-Up Studies Humans Intracranial Aneurysm - complications Intracranial Aneurysm - diagnostic imaging Intracranial Aneurysm - therapy Male Middle Aged Original Prospective Studies Subarachnoid Hemorrhage - complications Subarachnoid Hemorrhage - diagnostic imaging Subarachnoid Hemorrhage - therapy Treatment Outcome |
title | Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage? |
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