The Scientific and Therapeutic Rationale for Off‐Label Treatments in Amyotrophic Lateral Sclerosis

There are no dramatically effective pharmacological treatments for most patients with amyotrophic lateral sclerosis, a complex disease with multiple underlying mechanisms, such as neuroinflammation, oxidative stress, mitochondrial dysfunction, microbiome alteration, and antiretroviral activity. We s...

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Veröffentlicht in:	Annals of neurology 2025-01, Vol.97 (1), p.15-27
Hauptverfasser:	Bedlack, Richard, Li, Xiaoyan, Evangelista, Baggio Angelo, Panzetta, Maria E., Kwan, Justin, Gittings, Lauren M., Sattler, Rita
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Antiretroviral agents Drug therapy Labels Microbiomes Oxidative stress Review
Online-Zugang:	Volltext
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